Erythritol→Xylitol, cardiovascular research lineage of the same study
We have chronologically organized the results of repeated verification on sugar alcohol sweeteners by research teams affiliated with Cleveland Clinic and Charité University Hospital.
2023 · Erythritol correlation
Analysis of approximately 4,000 high-risk cardiovascular disease patients; high blood erythritol levels associated with approximately 2x higher risk of cardiovascular events within 3 years (Nature Medicine)
August 2024 · Erythritol intervention study
Healthy volunteers showed significantly increased platelet reactivity after consuming erythritol beverages (no change in sugar group)
2024 · Xylitol correlation (EHJ)
1,157 patients with history of cardiovascular disease + 2,149 in validation cohort; high concentration group showed significantly increased risk of cardiovascular events
August 2026 · ESC Xylitol general population cohort
17,710 general population (CLSA+EPIC-Norfolk); high concentration group risk CLSA +57%(6 years) / EPIC-Norfolk +18%(30 years)
Includes results at the conference presentation stage that have not yet been published in peer-reviewed journals.